Lonely:
abandoned, alone, apart, bummed out, by oneself, comfortless, companionless, deserted, desolate, destitute, disconsolate, down, empty, estranged, forsaken, friendless, godforsaken, homeless, isolated, left, lone, lonesome, outcast, reclusive, rejected, renounced, secluded, single, solitary, troglodytic, unattended, unbefriended, uncherished, unsocial, withdrawn
Exhausted:
beat*, bleary, bone-weary, bushed, crippled, crispy, dead*, dead tired*, debilitated, disabled, dog-tired*, done for*, done in*, drained, effete, enervated, frazzled, had it*, limp, outta gas*, played out, prostrated, run-down, sapped*, shot*, spent, tired out, wasted*, weak, weakened, wearied, worn, worn out
Restless:
active, agitated, antsy*, anxious, bustling, changeable, disturbed, edgy, fidgeting, fidgety, fitful, footloose*, fretful, hurried, inconstant, intermittent, irresolute, itchy*, jumpy, moving, nervous, nomadic, on edge, perturbed, restive, roving, sleepless, spasmodic, strung out*, transient, troubled, turbulent, uneasy, unpeaceful, unquiet, unrestful, unruly, unsettled, unstable, unsteady, wandering, worried
* = informal or slang
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